SK

Shyam Kamadolli

Venture Capital for Disruptive Science

Boston, Massachusetts

Invests in

  • Min Investment:

    $100,000.00
  • Max Investment:

    $5,000,000.00
  • Target Investment:

    $1,500,000.00

Work Experience

  • Managing Director

    2020

    At Fine Structure Ventures, an F-Prime Capital Fund (affiliated with FMR LLC, the parent company of Fidelity Investments), we back deep scientific and technical innovators raising Series-A/B/C rounds. Our VC fund is focused on revolutionary paradigms in next generation computing, energy/climate tech, biology, materials, and aerospace. Current investments include Commonwealth Fusion Systems (nuclear fusion), Mainspring Energy (on-site clean power generation), and Boston Metal (electrolytic extraction of steel).

  • Board Observer

    2024

  • Member Board Of Directors

    2020 - 2024

  • Managing Director - Fine Structure Ventures

    2024

    As of July 1, 2024, Fine Structure Ventures is an F-Prime fund.

  • Member Board Of Directors

    2020

2021

  • Board Observer / Investor

    2021

    Developer of a cell-free biomanufacturing technology and platform designed to create complex and high-value ingredients. The company's platform harnesses natural enzyme approaches to overcome cell limitations and provide a sustainable, low-cost, and consistent supply of natural ingredients, enabling clients to have access to sustainably produced ingredients.

  • Member Board Of Directors

    2021

  • Member Board of Directors

    2022

    The current generation of AI hardware (TPU, GPU, CPU) is not optimized for edge AI especially as the complexity of tasks and memory requirements increases. Femtosense has developed a 2D array of tightly coupled digital compute and memory blocks that exploit network sparsity coupled with an algorithm that trains networks to expose their underlying sparsity while maintaining performance. This coupled hardware and algorithm approach allows Femtosense to deliver the AI performance of large models in constrained edge platforms.

  • Member Board Of Directors

    2021

  • Member Board of Directors

    2024

    Radian is building a next-generation spaceplane planned to be the world's first single-stage-to-orbit, truly reusable space vehicle operating in Low Earth orbit.

  • Member Board of Directors

    2004

    At Constructive Bio, they rewrite the genome to build the biomolecules of the future. Their unique technology transforms living cells into biofactories, producing sustainable new materials and therapeutics. With complete control over the genetic sequence and code, they are exploring chemical space that natural biology has not previously accessed. Learn more at constructive.bio.

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