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Nnamdi Okike

Managing Partner and Co-Founder at 645 Ventures. Focused on investing in exceptional software and software-enabled companies.

San Francisco, California

Work Experience

  • Co-Founder and Managing Partner

    2013

    645 Ventures is an early-stage investment firm with over $550M AUM. We lead Seed and Series A rounds for software and software-enabled companies, and we work closely with exceptional teams to help them scale to the growth stage.

2024

  • Board Member

    2024

    ReflexAI brings the best in machine learning and natural language processing to mission-driven, people-centric organizations via innovative tools that transform how they train, develop, and empower their frontline teams.

2024

  • Board Observer

    2024

    Cube is the universal semantic layer that makes it easy to connect BI silos, embed analytics, and power your data apps and AI with context.

  • Board Member

    2022

    The NVCA empowers the next generation of American companies that will fuel the economy of tomorrow.

2024

  • Board Member

    2024

    Setpoint is a leading fintech that aims to streamline the hidden, cumbersome processes behind trillions in daily financial transactions. Backed by leading investors, Setpoint is pioneering the transformation of capital markets workflows from outdated manual systems to efficient, automated solutions, significantly reducing costs and enhancing speed for both borrowers and lenders. Founded in 2021, Setpoint’s capital and technology platform (Asset OS and Capital OS) enables auto, consumer, SMB, real estate and other asset-backed borrowers to grow profitably. Setpoint’s platform helps originators and lenders save time, reduce risk, and optimize for capital efficiency.

2022

  • Board Member

    2022

    Uptiq delivers an Enterprise AI Platform for the Banking, Wealth Management, and Fintech industries. By combining cutting-edge AI technology with compliant solutions, Uptiq helps financial institutions modernize their services, enhance operational efficiency, and deepen client relationships. With a particular emphasis on delivering reliable, accurate AI outputs, Uptiq’s technology is designed to avoid common LLM pitfalls like hallucinations, making it a trusted partner for highly regulated industries.

2021

  • Board Member

    2021

    Apty is a Digital Adoption Platform that helps enterprise optimize their business processes. Successful digital adoption involves both guiding people through new critical software applications and proactively pushing them to complete new processes. Only Apty combines the power of on-screen guidance with the time-saving automation of proactive process compliance. IT operation managers, Application Owners, VP HR/Sales, and leading CIOs alike all trust Apty to get the most out of their employees' use of web-based applications in their day-to-day job. Every month, nearly 1 million users use Apty to learn web-based apps and excel in their job in leading companies like Delta Airlines, Boeing, Agile CRM, and many more. Remember, the problem is not the software, it’s how you use it.

2020

  • Board Member

    2020

2019

  • Board Member

    2019

2018

  • Board Member

    2018

    Investor and board member of Negotiatus, a leading provider of SaaS e-procurement software for mid-market companies to large enterprises.